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Atrial Remodeling in Atrial Fibrillation. Comorbidities and Markers of Disease Progression Predict Catheter Ablation Outcome

[ Vol. 17 , Issue. 2 ]

Author(s):

Judit Szilágyi* and László Sághy   Pages 217 - 227 ( 11 )

Abstract:


Atrial fibrillation is the most common supraventricular arrhythmia affecting an increasing proportion of the population in which mainstream therapy, i.e. catheter ablation, provides freedom from arrhythmia in only a limited number of patients. Understanding the mechanism is key in order to find more effective therapies and to improve patient selection. In this review, the structural and electrophysiological changes of the atrial musculature that constitute atrial remodeling in atrial fibrillaton and how risk factors and markers of disease progression can predict catheter ablation outcome will be discussed in detail.

Keywords:

Atrial fibrillation, atrial remodeling, fibrosis, predictors of catheter ablation outcome, electrophysiological remodeling, scar imaging.

Affiliation:

2nd Department of Internal Medicine and Cardiology Centre, University of Szeged, Szeged, 2nd Department of Internal Medicine and Cardiology Centre, University of Szeged, Szeged



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