Sneha Nandy*, Siu-Hin Wan and Jorge Brenes-Salazar Pages 1 - 5 ( 5 )
Coronavirus disease 2019 (COVID-19) first emerged in a group of patients who presented with severe pneumonia in Wuhan, China in December 2019. A novel virus, now called SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) was isolated from lower respiratory tract samples. The current outbreak of infection has spread to over 100 countries and killed more 340,000 people as of 25th May, 2020. The predominant clinical manifestation of COVID-19 is respiratory disease- ranging from mild flu-like symptoms to fulminant pneumonia and Acute Respiratory Distress Syndrome (ARDS). Patients with pre-existing cardiovascular risk factors are considered more susceptible to the virus, and these conditions are often worsened by the infection. Further, COVID-19 infection has led to de novo cardiac complications like acute myocardial injury and arrhythmias. In this review, we have focused on the cardiovascular manifestations of COVID-19 infection that have been reported in literature so far. We have also outlined the effect of pre-existing cardiovascular disease and well as risk factors on the clinical course and outcomes of COVID-19 infection.
COVID-19, cardiovascular, cardiac, coronavirus, SARS-CoV-2, infection
Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905,, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905,, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905